Santi Vincenzo e Anastasio a Trevi in Rome was designed by Martino Longhi the Younger and rebuilt on the order of Cardinal Mazarin, whose coat of arms is the focus of the facade. Construction ran from 1646 to 1650, though a reference title gives the facade as 1646 to 1660. The style is Baroque. The church had served as the parish church for the Quirinal Palace.
The travertine facade has two superimposed entablatures, broken pediments and Corinthian columns. The text cites eighteen fully disengaged columns, which earned the nickname the canebrake. A central female mascaron is rumored to depict Marie Mancini. Restoration in 1989 and 1990 was needed because the travertine proved porous.
A medieval church on the site is mentioned in 962. This church preserves the embalmed hearts and precordia of 22 popes, from Sixtus V to Leo XIII. The article gives no hours.

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