A fire destroyed the church in 1519. Jacopo Sansovino drew the rebuilding plan but left Rome during the Sack of 1527, and Antonio da Sangallo the Younger continued the work. Rebuilding funds were used to bribe the landsknechts during the Sack, and a Tiber flood damaged the rebuilt church in 1530. The article says it was rebuilt in its present form in the late 16th and early 17th centuries.
Monsignor Marcantonio Cataldi Boncompagni commissioned the facade, which Carlo Fontana designed and built from 1692 to 1697. It has travertine statues by Francesco Cavallini. The style is Baroque, with late Baroque interior decoration. The main altar has 12th-century opus sectile.
The Servite Order owns and administers it, and it is the headquarters of the Servite General Curia. Their service dates to 1369 or 1375.
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