A Romanesque church for foreign merchants stood on the site in the 11th century, and an early Gothic church replaced it in 1256. Construction of the present church began in the 14th century, was almost complete by the early 15th century except for the towers, gable and roof, and ended in the 1450s. The gable and north tower were finished under George of Poděbrady. Matěj Rejsek is credited with the south tower, completed in 1511.
The late Gothic church has a three-aisled nave and two western towers, each 262 feet (80 m) high with octagonal spires. The article says the north portal's Passion relief is an important example of pre-Hussite Gothic sculpture.
Inside are a stone baldaquin of 1493, a 1414 baptistery called the oldest and largest in Prague, and the tombstone of Tycho Brahe. The main entrance is through a narrow passage between houses.

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